University of Colorado Colorado Springs

Resolution enhancement for sparse single-cell Hi-C contact matrices, using a cascading residual GAN with self-attention over chromatin loci.

Hi-C contact map super-resolution that adds interaction frequencies imputed from DNase-seq accessibility so one cell line's model transfers to others.

Resolution enhancement for Hi-C contact matrices, reconstructing full-depth 10 kb maps from libraries sequenced at a fraction of the read depth.