Université Paris-Saclay

Genomic variant effect prediction from a bidirectional absorbing-diffusion model over human DNA, pretrained with entropy-guided span masking.

Bulk RNA-seq foundation model that learns patient-level embeddings from binned gene expression for pan-cancer classification and survival prediction.

RNA backbone torsion and pseudo-torsion angle prediction from sequence alone, built by fine-tuning a DNABERT checkpoint on solved RNA structures.

Frugal conditional diffusion model that samples human SNP haplotypes in PCA space, producing artificial genomes for a chosen continental ancestry.

Graph attention foundation model for spatial transcriptomics that assigns spatial domains zero-shot across gene panels, tissues, and technologies.

A Wasserstein GAN that generates artificial human genomes in PCA space, synthesizing 65,535-SNP haplotypes for 26 worldwide populations.