OpenBind Consortium / Aqlaboratory / Columbia University / OpenFold Consortium / Diamond Light Source / University of Oxford
Released August 21, 2026
Protein-ligand co-folding model on the OpenFold3 architecture, trained on PDB structures through June 2025 with inference-time chemical steering.
Aqlaboratory / OpenFold Consortium / Lawrence Livermore National Laboratory / Seoul National University / Novo Nordisk / Amazon Web Services / Chan Zuckerberg Initiative / Absci / SandboxAQ / AMD / NVIDIA / University of Bristol / Pfizer
Released October 28, 2025
Open-source Apache-2.0 reproduction of AlphaFold3 that predicts all-atom structures of proteins, RNA, DNA, small molecules, and their complexes.