Labs & Groups (1)
Models (5)
VirtualCRISPR
Chan Zuckerberg Biohub Chicago / Northwestern University / University of Chicago
Released February 28, 2026
Large language model trained on functional genomics data to prioritize novel therapeutic targets from genome-wide CRISPR knockout screens.
GenomeOcean
DOE Joint Genome Institute / Northwestern University / Johns Hopkins University / University of California, Merced / University of California, Berkeley / Miami University / Illumina
Released February 5, 2025
4B-parameter generative genome foundation model trained on assembled environmental metagenomes for microbial representation and de novo DNA design.
DNA embedding model built on DNABERT-2, using contrastive learning to cluster sequences by species for metagenomic binning without labeled data.
Multi-species genomic foundation model swapping k-mer tokenization for byte pair encoding, matching Nucleotide Transformer with 21x fewer parameters.
Bidirectional transformer for DNA using k-mer tokenization, fine-tunable for promoter, splice site, and transcription factor binding prediction.