Jiangnan University / Shanghai Jiao Tong University / Macquarie University / Nantong University / Shandong Huatai Paper / Shandong Yellow Triangle Biotechnology Industry Research Institute
Released July 26, 2025
Enzyme thermostability prediction from sequence, using segment-level attention over ESM-2 embeddings to rank mutation sites for protein engineering.
PROTAC degrader generation pipeline that screens target-binding fragments, then builds molecules under structure and physicochemical constraints.
Zhejiang University / First Affiliated Hospital, Zhejiang University School of Medicine / Nanhu Brain-computer Interface Institute / Liangzhu Laboratory / Lingang Laboratory / Nantong University
Released October 11, 2024
AAV capsid design platform for gene therapy that steers a peptide language model toward inserts combining receptor targeting and production fitness.