King's College London

RNA foundation model pretrained on 223 eCLIP experiments to predict base-resolution RBP binding, with frozen embeddings that transfer downstream.

Histopathology model predicting homologous recombination deficiency from H&E slides in ovarian cancer, reaching 0.846 AUC and 0.938 specificity.

Zero-shot pathogenicity scoring for in-frame insertions and deletions from protein language model likelihoods over residues both alleles share.

Antibody chain pairing model that scores whether a heavy and a light chain are cognate partners, fine-tuned from an antibody-specific language model.

Crossmodal diffusion model synthesizing bulk tumor gene expression from H&E whole-slide images, so grading and survival prediction need no RNA assay.

Cell Painting generative model encoding lab, batch, and well position as causal variables, predicting mechanism and target for unseen compounds.

Neural spike decoding model whose Hebbian self-attention yields interpretable low-dimensional embeddings of electrophysiology and calcium imaging.

Cryo-electron tomography membrane analysis pipeline pairing generalizable U-Net membrane segmentation with mesh-based particle localization.