Insilico Medicine

Small-molecule drug discovery foundation model covering ADMET, retrosynthesis, drug-target activity, and molecular optimization in a 2.6B checkpoint.

Generative chemistry foundation model pairing a text-and-SMILES language backbone with a 3D molecular point-cloud encoder for prediction and design.

Conditional generator of bulk transcriptome and DNA methylation profiles, sampling tissue-, age- and species-matched synthetic omics samples.

Multi-omics transformer generating transcriptomic, methylation and proteomic signatures for a given tissue, disease, age group, sex and compound.

Multimodal aging clock predicting chronological age from DNA methylation or bulk RNA-seq, with a frozen backbone reused for disease target discovery.