Indraprastha Institute of Information Technology Delhi / Aurigene Oncology
Released August 28, 2025
Protein degrader design framework that mines fragment-target data to build PROTACs and predicts degradation potency (DC50) and maximal degradation.
Anticancer protein prediction from sequence with a fine-tuned ESM-2 650M classifier; a BLAST hybrid raises validation AUC to 0.91.
Neurotoxicity prediction for short peptides and full-length neurotoxins, with separate ESM-2 models matched to each sequence length regime.
Melting-temperature regressor over frozen ProtBert embeddings that scans every single-point mutant of a sequence to hit a target Tm.