The Hospital for Sick Children

Single-cell foundation model pretrained on human brain organoids that predicts transcriptome-wide responses to knockdown of any protein-coding gene.

Synthesizable 3D molecule generation that jointly samples building blocks, reactions, and atomic coordinates, returning a synthesis route per design.

Protein segmentation that locates folded domain, sub-domain, and disordered region boundaries from frozen ProtT5 embeddings without any training step.