Helixon Research

Molecular docking framework that poses several ligands sharing one protein pocket at once, using their consistency to sharpen each prediction.

Peptide binder design by mimicking the binding interface of a known receptor or antibody, generating all-atom peptides through latent diffusion.

Antibody CDR sequence-structure co-design by flow matching, starting from an informative structural prior rather than from Gaussian noise.

Target-conditioned peptide binder design model that samples hot-spot residues from an energy-based density, then extends fragments autoregressively.

Full-atom peptide binder design against a target pocket, generating backbone frames, side-chain torsions and residue types in one joint flow.