Harbin Institute of Technology

De novo small-molecule generation conditioned on disease-reversal gene expression, with a contrastive transcriptome encoder steering a MolT5 decoder.

miRNA-target interaction model fusing five gated evidence experts, whose frozen representation transfers to siRNA efficacy prediction.

Protein-protein interface prediction from 3D structure using face-centered surface fingerprints and geometric graph attention, at ROC AUC 0.89.

Protein function prediction that assigns Gene Ontology terms from predicted 3D structure, ESM-2 embeddings, and cross-species network propagation.

Single-cell foundation model that fuses scRNA-seq profiles with text, pairing a cell encoder with an LLM for cell annotation and clustering.

EEG foundation model whose dual objective aligns masked-patch features with whole-signal features, then transfers to new montages by linear probe.