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A national genomics research institute under A*STAR, spanning sequencing, computational genomics, single-cell platforms, and precision medicine.
Agency for Science, Technology and Research (A*STAR) / Bioinformatics Institute (A*STAR) / Genome Institute of Singapore / Aalborg University / Imperial College London / Statens Serum Institut / University of Copenhagen
Released September 9, 2026
RNA 3D structure evaluator that ranks candidate conformations without a reference. Sequence conditioning comes from a frozen RNA language model.
Duke-NUS Medical School / Genome Institute of Singapore / National University of Singapore / National Cancer Centre Singapore / Yale University
Released September 19, 2025
Single-cell foundation model domain-adapting Llama-3.1-8B on 1.3M gastric cancer cells with gene-family cell sentences instead of ranked-gene order.
National University of Singapore / Genome Institute of Singapore / University of Zagreb
Released September 18, 2025
Diploid de novo genome assembly that scores assembly-graph edges with a graph neural network and reconstructs phased haplotypes by beam search.
RNA language model built on the xLSTM recurrent architecture instead of a transformer backbone, pretrained on RNAcentral with 33.7M parameters.
Genome Institute of Singapore / Institute of Bioengineering and Bioimaging (IBB) / Xenolis / National University of Singapore
Released December 2, 2024
Nanopore basecaller extending Bonito to a six-letter alphabet, reading the unnatural bases Ds and Px alongside canonical A, T, C and G.