Capital Medical University

SE(3)-equivariant chemical language model for pocket-based 3D molecule generation, used to design an HPK1 inhibitor with in vivo anti-tumor efficacy.

Antibiotic resistance gene detection in metagenomes, pairing frozen ESM-1v embeddings with light classifier heads for drug class and mechanism.

Molecular docking and design foundation model that unifies structure-based drug design and peptide design at the atom level in one checkpoint.

Universal brain lesion segmentation for multi-modal brain MRI, using a Mixture of Modality Experts to span diverse modalities and lesion types.

Vision-language model for annotation-free pathology localization, marking the finding a text prompt names in X-ray, histology and fundus images.