ByteDance Research

Two-stage backbone generator that designs protein domains separately, then weaves them into one long chain with an SE(3) diffusion assembly module.

Multimodal discrete-diffusion protein language model that co-generates amino acid sequence and 3D backbone structure from a single transformer.

Discrete-diffusion protein language model pretrained on UniRef50 that generates sequences and gives embeddings that outperform ESM-2 on prediction.