Agency for Science, Technology and Research (A*STAR)

RNA 3D structure evaluator that ranks candidate conformations without a reference. Sequence conditioning comes from a frozen RNA language model.

Infers gene-centered chromatin interactions from bulk RNA-seq alone, mapping 3D genome changes across 12,347 tumor and normal transcriptomes.

Histopathology model reconstructing tissue-wide single-cell gene expression from H&E slides, using sparse TMA measurements as molecular anchors.

Self-supervised medical imaging foundation model pretrained on 3.3 million CT, X-ray, ultrasound, pathology, OCT, fundus, and dermoscopy images.

Cross-modal co-embedding of biosynthetic gene clusters and natural products, enabling bidirectional retrieval between gene cluster and compound.

Ophthalmic foundation model behind the GlobeReady platform, reading fundus and OCT scans by frozen-encoder retrieval instead of per-site fine-tuning.

PROTAC degradation prediction from molecular graphs of the target, linker, and E3 ligase, combining cross-attention with contrastive learning.

Chromatin interaction prediction from DNA sequence alone, calling CTCF-, RNA Pol II- and Hi-C-associated loops between open chromatin regions.