All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 121 of 21 filtered models

  • DrugGen 2

    6834
    Isfahan University of Medical SciencesJuly 9, 2026de_novo_designdrug_discoverylanguage_model+4

    Generative language model that designs drug-like SMILES conditioned on disease ontology and a target protein sequence for de novo drug discovery.

    Small moleculeProtein
    51Openness
  • Washington University in St. LouisJune 22, 2026cell_biologycell_type_annotationgene_expression+5

    Single-cell language model that prepends biomedical knowledge-graph tokens to cell sentences, grounding cell type annotation in pathway structure.

    Single-cellLanguage model
    23Openness
  • RNAJog

    2
    Shanghai Jiao Tong UniversityJune 20, 2026autoregressivecodoncodon_optimization+7

    Autoregressive generative model that uses reinforcement learning to optimize mRNA codon sequences for MFE, CAI, and GC content.

    RNA
    9Openness
  • RNARL

    Shanghai Jiao Tong University +2 othersJune 13, 2026codoncodon_optimizationgenerative+6

    Reinforcement-learning generative framework for multi-objective RNA codon optimization that generalizes across six species and five RNA types.

    RNA
    4Openness
  • GermRL

    14
    Johns Hopkins UniversityJune 11, 2026antibodyantibody_designde_novo_design+6

    Reinforcement learning framework that fine-tunes the ProGen2-OAS antibody language model with GRPO to cut germline bias in generated sequences.

    Protein
    65Openness
  • PlasmidLM

    2
    University College LondonMay 19, 2026dnalanguage_modelplasmid_design+4

    Promptable DNA language model that generates multi-kilobase plasmid sequences from plain-language component specs, refined with verifiable rewards.

    DNA & Gene
    49Openness
  • RVQ-Alpha

    Guangzhou National LaboratoryApril 23, 2026cell_type_annotationlanguage_modelmultimodal+3

    Single-cell foundation model that tokenizes scRNA-seq into 10 tokens in a Qwen3-4B vocabulary for cell type annotation and perturbation prediction.

    Single-cell
    4Openness
  • GPT-Rosalind

    4.7K
    OpenAIApril 16, 2026dnadrug_discoveryfoundation_model+9

    OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.

    Language model
    5Openness
  • Chinese Academy of SciencesApril 2, 2026codoncodon_optimizationfoundation_model+8

    Autoregressive model for therapeutic mRNA design that jointly generates 5' UTR, CDS, and 3' UTR, pretrained on 30 million full-length natural mRNAs.

    RNA
    10Openness
  • Arc Institute +3 othersMarch 20, 2026go_term_annotationlarge_language_modelmultimodal+5

    Multimodal reasoning LLM for protein function prediction, fusing protein language model embeddings to emit interpretable GO-term reasoning traces.

    ProteinLanguage model
    58Openness
  • Pengcheng Laboratory +2 othersMarch 13, 2026chain_of_thoughtcheminformaticsdrug_discovery+6

    Molecular reasoning model built on DeepSeek-7B, using chain-of-thought and reinforcement learning for property prediction, generation, and reactions.

    Small moleculeLanguage model
    21Openness
  • SynPROTAC

    Sun Yat-sen UniversityDecember 12, 2025de_novo_designdrug_discoverygenerative+3

    Designs synthesizable PROTAC degraders from reaction templates and purchasable building blocks, with reinforcement learning tuning the generator.

    Small molecule
    11Openness
  • FcGPT

    ETH ZurichOctober 11, 2025antibodyde_novo_designgenerative+4

    Autoregressive protein language model for antibody Fc domains, reinforcement-tuned to design variants with programmable Fc-receptor binding profiles.

    Protein
    20Openness
  • OwkinZero

    1
    OwkinAugust 22, 2025drug_discoveryfoundation_modelreinforcement_learning+2

    Biological reasoning language model that post-trains Qwen3 with reinforcement learning from verifiable rewards for drug-discovery tasks.

    Language model
    15Openness
  • rBio

    14616
    Chan Zuckerberg InitiativeAugust 18, 2025cell_biologyfoundation_modelreinforcement_learning+2

    Reasoning language model post-trained on virtual cell simulations, answering questions about gene perturbations and their effects in natural language.

    Language model
    60Openness
  • Lingshu

    3198144.7K
    DAMO Academy +1 otherJune 8, 2025clinical_reasoningfoundation_modelhistology+7

    Generalist medical multimodal LLM for image understanding, visual question answering, and report generation across twelve-plus imaging modalities.

    ImagingLanguage model
    70Openness
  • QoQ-Med

    5238465
    MITMay 31, 2025ecgfoundation_modelhistology+7

    Multimodal clinical foundation model reasoning jointly over 2D and 3D medical images, ECG time-series, and text reports across nine clinical domains.

    ImagingBiosignalsLanguage model
    74Openness
  • GMAI-VL-R1

    1929
    Shanghai AI Laboratory +6 othersApril 2, 2025histologylanguage_modelmedical_image_diagnosis+7

    General medical vision-language model trained with reinforcement learning to reason step by step over medical images for diagnosis and visual QA.

    ImagingLanguage model
    17Openness
  • Med-R1

    128140
    Emory University +4 othersMarch 18, 2025disease_diagnosisgenerativehistology+7

    Medical vision-language model trained with reinforcement learning for generalizable reasoning across eight imaging modalities and five question types.

    ImagingLanguage model
    45Openness
  • MedVLM-R1

    321911.2K
    Technical University of Munich +2 othersFebruary 26, 2025medical_reasoningmultimodalradiology+4

    2B-parameter medical vision-language model that uses reinforcement learning to show interpretable reasoning for radiology visual question answering.

    ImagingLanguage model
    83Openness
  • MINIM

    158138
    Peking University +2 othersFebruary 1, 2025data_augmentationdiffusionfoundation_model+9

    Text-to-image diffusion model that generates synthetic medical images across imaging modalities and organs to augment scarce clinical training data.

    Imaging
    41Openness