All Competitors

Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.

Flow-matching generative model for de novo atomistic protein binder design against protein and small-molecule targets, including carbohydrate binders.

Partially latent flow-matching model for de novo protein design, jointly generating sequence and all-atom structure for proteins up to 800 residues.

All-atom protein design diffusion model conditioned on ligands, nucleic acids, and other non-protein atoms, supporting enzyme and DNA binder design.

All-atom protein representation model that learns from each residue's strictly local atomic neighborhood, capturing side-chain geometry and chemistry.