All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 265288 of 518 filtered models

  • SIGMMA

    1
    Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7

    Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.

    PathologySpatial omics
    20Openness
  • Uni-Hema

    1
    Information Technology University of the Punjab +1 otherNovember 18, 2025classificationcnnfoundation_model+8

    Digital hematopathology foundation model unifying blood-cell detection, classification, segmentation, and visual question answering.

    Pathology
    8Openness
  • MergeDNA

    5
    Westlake University +1 otherNovember 17, 2025foundation_modelgenomicsmulti_omics+6

    Hierarchical DNA foundation model that co-trains a dynamic token-merging tokenizer with latent Transformers to match genomic information density.

    DNA & Gene
    5Openness
  • UniLingo3DMol

    StoneWiseNovember 14, 2025de_novo_designdrug_discoverygenerative+5

    Pretrained language model for 3D molecule generation in protein pockets, unifying de novo and fragment-based drug design in one multi-task framework.

    Small molecule
    8Openness
  • ConformAb

    1
    GenentechNovember 13, 2025antibodyantibody_designdiffusion+5

    Guided discrete diffusion model for antibody lead optimization, conditioning sequence design on the seed binder's CDR canonical backbone conformation.

    Protein
    18Openness
  • E1

    1131115.2K
    ProfluentNovember 13, 2025contact_predictionfoundation_modelproteomics+6

    Retrieval-augmented protein encoders that fuse homologous sequences into a single-pass transformer for variant effect and contact prediction.

    Protein
    47Openness
  • Technical University of MunichNovember 10, 2025mass_spectrometryproteomicsptm_localization+3

    Spectral prediction model for modified peptides, forecasting fragment-ion intensities and retention time with zero-shot generalization to unseen PTMs.

    Protein
    30Openness
  • New York UniversityNovember 10, 2025cnndrug_discoverygraph_neural_network+8

    Multimodal conversational LLM for metabolite analysis, fusing a molecular-graph GNN and molecular-image CNN with a Vicuna-13B language backbone.

    MetabolomicsSmall molecule
    48Openness
  • TEMPO

    5
    Chinese University of Hong Kong, Shenzhen +1 otherNovember 7, 2025autoregressiveconformational_ensemble_generationgenerative+4

    Protein dynamics model that samples conformational ensembles autoregressively at slow and fast timescales, generalizing zero-shot to unseen proteins.

    Protein
    25Openness
  • Nona

    3
    GenentechNovember 6, 2025discrete_diffusionfoundation_modelfunctional_genomics+8

    Genomics foundation model that unifies sequence-to-function prediction, DNA language modeling, and generative regulatory design in one backbone.

    DNA & GeneRNA
    8Openness
  • EvoSynth

    8
    University of Alabama at BirminghamNovember 4, 2025autoencoderde_novo_designdiffusion+6

    Multi-target drug discovery framework pairing a diffusion-transformer generator with evolutionary latent-space search and synthesis-aware scoring.

    Small molecule
    51Openness
  • University of VirginiaNovember 4, 2025batch_correctioncell_type_annotationchromatin+7

    Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.

    Single-cellDNA & Gene
    32Openness
  • scLDM

    587
    Chan Zuckerberg InitiativeNovember 4, 2025autoencodercell_biologydata_augmentation+8

    Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.

    Single-cell
    75Openness
  • scLDM.CD4

    9198
    Chan Zuckerberg InitiativeNovember 4, 2025autoencodercell_biologydiffusion+7

    Single-cell latent diffusion model fine-tuned on 14.5 million CD4+ T cells to simulate transcriptomic effects of single-gene perturbations.

    Single-cell
    75Openness
  • H3BERTa

    1201
    University of BernNovember 3, 2025antibodyantibody_repertoire_analysisbert+8

    Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.

    ProteinLanguage model
    83Openness
  • Chan Zuckerberg Initiative +1 otherNovember 2, 2025dnafoundation_modelgene_expression+4

    Hierarchical transformer with 1.2 billion parameters that predicts personalized gene expression from diploid genomes for variant effect prediction.

    DNA & Gene
    68Openness
  • GPFM

    12954
    Hong Kong University of Science and Technology +3 othersNovember 1, 2025cancer_diagnosisfeature_extractionfoundation_model+8

    Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.

    Pathology
    84Openness
  • Boston UniversityOctober 31, 2025antibodybinding_affinity_predictionlanguage_model+4

    Paired heavy/light antibody language model fine-tuning ESM-2 and ESM-C with CDR-preferential masking for zero-shot binding affinity embeddings.

    Protein
    8Openness
  • MolChord

    2
    Beijing Zhongguancun Academy +1 otherOctober 31, 2025de_novo_designdiffusiondrug_discovery+4

    Structure-based drug design model that generates ligands for a protein pocket, pairing a diffusion structure encoder with preference optimization.

    Small moleculeProtein
    23Openness
  • Albert Einstein College of MedicineOctober 30, 2025antibodyantibody_designembeddings+5

    Structure-based conformational B-cell epitope predictor that scores local antigen surface patches with ESM-2 embeddings and an ensemble MLP.

    Protein
    12Openness
  • LSM-MS2

    Matterworks, Inc.October 30, 2025compound_annotationdisease_classificationembeddings+7

    Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.

    MetabolomicsSmall molecule
    4Openness
  • Harvard Medical SchoolOctober 27, 2025embeddingsrepresentation_learningsiamese_network+1

    Siamese protein language model whose embedding distances approximate TM-score and lDDT, enabling alignment-free protein structure comparison.

    Protein
    5Openness
  • LUNA

    131176.3K
    ETH ZurichOctober 25, 2025abnormality_detectionartifact_rejectioncross_attention+5

    EEG foundation model whose learned queries map any electrode montage into a fixed latent space, scaling linearly in the number of channels.

    Biosignals
    73Openness
  • Verily Life SciencesOctober 24, 2025cross_attentiondisease_risk_predictionelectronic_health_records+7

    Multimodal EHR foundation model that fuses polygenic risk scores into a GPT-2-style backbone by cross-attention for zero-shot disease risk prediction.

    Language modelDNA & Gene
    8Openness