All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 1–6 of 6 filtered models

  • Nesso-1

    96——
    Recursion PharmaceuticalsJuly 20, 2026binding_affinity_predictiondrug_discoverymulti_task+3

    Protein-ligand binding affinity prediction from sequence and SMILES, without MSAs. Coarse-grained cofolding runs over 10x faster than Boltz-2.

    ProteinSmall molecule
    72Openness

  • MACE-POLAR-1

    —15—
    University of CambridgeFebruary 23, 2026drug_discoveryequivariant_neural_networkfoundation_model+5

    Polarizable machine-learning interatomic potential extending MACE with long-range electrostatics, trained on 100M OMol25 DFT calculations.

    Small moleculeProtein
    19Openness

  • BioKinema

    —3—
    International Digital Economy AcademyFebruary 15, 2026conformational_samplingdiffusiondrug_discovery+5

    Diffusion model that generates continuous-time, all-atom biomolecular trajectories, reproducing conformational kinetics far more cheaply than MD.

    ProteinSmall molecule
    13Openness

  • AtomPaint

    ———
    Harvard Medical SchoolFebruary 4, 2026binder_designdiffusiongenerative+4

    Full-atom SE(3)-equivariant diffusion model that inpaints binding interfaces to design proteins that bind DNA, RNA, and small molecules.

    ProteinSmall molecule
    19Openness

  • OMTRA

    67——
    University of Pittsburgh +1 otherDecember 4, 2025conformer_generationde_novo_designdrug_discovery+8

    Structure-based drug design model that unifies de novo generation, docking, conformer generation, and pharmacophore conditioning via flow matching.

    Small moleculeProtein
    72Openness

  • EiRA

    —2—
    Hunan UniversitySeptember 2, 2025binder_designdnagenerative+6

    Protein binder design model post-trained from a multimodal protein language model to bind proteins, peptides, small molecules, and nucleic acids.

    Protein
    13Openness