All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 118 filtered models

  • Hong Kong University of Science and Technology +4 othersJune 18, 2026foundation_modelself_supervisedtransfer_learning+1

    NMR foundation model trained on 158 million simulated 1H and 13C spectra, transferring simulation-learned representations to real experimental data.

    Small moleculeMetabolomics
    43Openness
  • GENATATOR

    23
    AIRI InstituteJune 17, 2026gene_annotationgene_structure_predictiontransfer_learning+2

    Ab initio gene annotation model that predicts gene boundaries and exon-intron structure from raw DNA, generalizing zero-shot to unseen species.

    DNA & GeneRNA
    22Openness
  • CREP

    University of OxfordJune 7, 2026cis_regulatory_element_annotationdnaregulatory_genomics+4

    Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.

    DNA & Gene
    8Openness
  • Cellpin

    Technical University of MunichJune 5, 2026denoisinggene_imputationsingle_cell+4

    Variational autoencoder trained on scRNA-seq and applied frozen to impute unmeasured genes and denoise spatial transcriptomics profiles.

    Spatial omicsSingle-cell
    22Openness
  • BrainGFM

    173
    Lehigh University +1 otherJune 2, 2026brain_connectomedisorder_classificationfmri+7

    Graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero-shot disorder classification.

    Biosignals
    16Openness
  • CryoProt

    Hunan University +1 otherJune 1, 2026active_site_identificationbinding_affinitycryo_em+7

    Protein representation learning from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.

    ImagingProtein
    11Openness
  • DanioDecima

    Biohub +1 otherMay 29, 2026cnnde_novo_designdna+7

    Zebrafish sequence-to-function model predicting cell-type-specific gene expression from DNA sequence across embryonic development.

    DNA & GeneSingle-cell
    22Openness
  • FlowTransOP

    MIT +2 othersMay 27, 2026autoencodercross_domain_translationcross_species+7

    Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.

    Single-cell
    87Openness
  • Hong Kong University of Science and Technology +9 othersMay 25, 2026foundation_modelself_supervisedtransfer_learning+2

    Lung pathology foundation model adapted from Virchow2 on whole-slide images, validated across 32 tasks spanning the lung diagnostic workflow.

    Pathology
    5Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.

    RNA
    11Openness
  • University of FloridaMay 18, 2026bertbilstmcnn+11

    Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.

    DNA & Gene
    45Openness
  • University of CopenhagenMay 14, 2026foundation_modelsegmentationtransfer_learning+2

    Domain-specific foundation model for zero-shot plant root image segmentation, built on a MobileSAM backbone and trained across nine root datasets.

    Imaging
    74Openness
  • SpaRank

    Guangxi UniversityMay 13, 2026foundation_modelmultimodalspatial_transcriptomics+2

    Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.

    Spatial omics
    8Openness
  • ConvergeCELL

    34
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • University of Naples Federico II +1 otherMay 5, 2026de_novo_designgenerativeprotein_design+2

    Three fixed ProtGPT2 fine-tunes specialized for metalloprotein generation, trained on ProteinMPNN-derived synthetic sequences.

    Protein
    38Openness
  • CoMole

    University of Notre DameMay 1, 2026de_novo_designdiffusiondrug_discovery+7

    Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.

    Small molecule
    23Openness
  • HyperMap

    1
    University of California, San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.

    Single-cell
    11Openness
  • AF2Dock

    151
    Johns Hopkins University +1 otherApril 24, 2026antibodyflow_matchinggenerative+5

    Protein-protein docking model adapting AlphaFold-Multimer with a docking module and flow-matching training to assemble subunits without MSAs.

    Protein
    77Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • muat

    8
    University of HelsinkiApril 3, 2026attentioncancer_genomicsrepresentation_learning+5

    Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.

    DNA & Gene
    65Openness
  • Carnegie Mellon UniversityMarch 27, 2026brain_computer_interfaceeegfoundation_model+5

    EEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.

    Biosignals
    18Openness
  • ZeroFold

    University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3

    Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.

    RNAProtein
    23Openness
  • CLIPepPI

    2
    Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5

    Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.

    Protein
    50Openness
  • HERCULES

    Italian Institute of TechnologyMarch 17, 2026multi_taskproteomicsrna_binding_prediction+4

    Protein language model that classifies RNA-binding proteins, localizes RNA-binding domains, and scores mutation effects at single-residue resolution.

    Protein
    44Openness