All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 85 filtered models

  • CREP

    University of OxfordJune 7, 2026cis_regulatory_element_annotationdnaregulatory_genomics+4

    Fine-tuned Enformer derivative that predicts discrete, interpretable cis-regulatory element class annotations (enhancer, promoter, insulator) directly from DNA sequence across human cell types.

    DNA & Gene
    8Openness
  • Cellpin

    Technical University of MunichJune 5, 2026denoisinggene_imputationsingle_cell+4

    A VAE trained on scRNA-seq reference data and applied frozen at inference to impute unmeasured genes and denoise spatial transcriptomics profiles.

    Spatial omicsSingle-cell
    22Openness
  • BrainGFM

    173
    Lehigh University +1 otherJune 2, 2026brain_connectomedisorder_classificationfmri+7

    A graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero/few-shot generalization to unseen disorders.

    Biosignals
    16Openness
  • CryoProt

    Hunan University +1 otherJune 1, 2026active_site_identificationbinding_affinitycryo_em+7

    Protein pretraining framework that learns representations directly from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.

    ImagingProtein
    11Openness
  • DanioDecima

    Chan Zuckerberg BiohubMay 29, 2026cnnde_novo_designdna+7

    A zebrafish DNA sequence-to-function model predicting cell-type-specific single-cell expression across 85 cell-type x developmental-timepoint combinations during embryogenesis.

    DNA & GeneSingle-cell
    22Openness
  • FlowTransOP

    MIT +2 othersMay 27, 2026autoencodercross_domain_translationcross_species+7

    A constrained deep flow-matching framework for distributional translation of omics signatures across biological domains, such as mouse-to-human transcriptomics, without paired samples.

    Single-cell
    87Openness
  • Hong Kong University of Science and Technology +9 othersMay 25, 2026clinical_decision_supportfoundation_modellung_tissue+7

    A subspecialty lung-pathology foundation model, fine-tuned from Virchow2 and prospectively validated across 32 clinical tasks spanning the lung diagnostic workflow.

    Pathology
    5Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    A cross-modal transfer-learning model that adapts the ESM-2 650M protein language model to mRNA analysis by swapping amino-acid tokens for codon tokens, applied to mRNA benchmarks without re-training.

    RNA
    11Openness
  • University of FloridaMay 18, 2026bertbilstmcnn+11

    Multimodal deep-learning framework that detects and localizes DNA lesions directly from native nanopore sequencing, built on the damage-aware LesionBERT foundation model.

    DNA & Gene
    45Openness
  • University of CopenhagenMay 14, 2026foundation_modelplant_phenotypingsegmentation+3

    A domain-specific foundation model for zero-shot plant root image segmentation, built on a MobileSAM backbone and trained across nine diverse root datasets.

    Imaging
    74Openness
  • SpaRank

    Guangxi UniversityMay 13, 2026cell_type_deconvolutionfoundation_modelmultimodal+3

    A transferable spatial-transcriptomics deconvolution model whose rank-based spot encoding lets one pretrained model generalize across tissues, disease states, and platforms without retraining.

    Spatial omics
    8Openness
  • ConvergeCELL

    59
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    A virtual cell foundation model pretrained on 23M+ cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • University of Naples Federico II +1 otherMay 5, 2026de_novo_designgenerativemetalloprotein+3

    Three fixed ProtGPT2 fine-tunes specialized for metalloprotein generation, trained on ProteinMPNN-derived synthetic sequences.

    Protein
    38Openness
  • CoMole

    University of Notre DameMay 1, 2026de_novo_designdiffusiondrug_discovery+7

    A motif-aware graph diffusion transformer for controllable molecular generation that transfers to unseen properties by learning only lightweight task embeddings with the generator frozen.

    Small molecule
    23Openness
  • HyperMap

    University of California San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few seed perturbations, using one-eighth the parameters of typical single-cell foundation models.

    Single-cell
    11Openness
  • AF2Dock

    141
    Johns Hopkins University +1 otherApril 24, 2026antibodyflow_matchinggenerative+5

    A generative protein-protein docking model that adapts AlphaFold-Multimer via flow matching, replacing the template module with a docking module.

    Protein
    77Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    A supervised, chromatin-informed foundation model that predicts regulatory activity directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • muat

    8
    University of HelsinkiApril 3, 2026attentioncancer_genomicsrepresentation_learning+5

    A portable transformer that classifies tumour types and learns representations from somatic variants, with auto-downloading WGS and WES checkpoints.

    DNA & Gene
    65Openness
  • Carnegie Mellon UniversityMarch 27, 2026brain_computer_interfaceeegfoundation_model+5

    EEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.

    Biosignals
    18Openness
  • ZeroFold

    University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3

    A transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, without requiring predicted structures.

    RNAProtein
    23Openness
  • CLIPepPI

    1
    Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5

    Dual-encoder contrastive model that embeds protein domains and peptides into a shared space to predict domain-peptide binding specificity at proteome scale.

    Protein
    50Openness
  • HERCULES

    Italian Institute of TechnologyMarch 17, 2026multi_taskproteomicsrna_binding_prediction+4

    Protein language model that predicts RNA-binding domains, global RNA-binding propensity, and mutation effects at single-residue resolution from sequence.

    Protein
    44Openness
  • ESMRank

    TIGEMFebruary 26, 2026deep_mutational_scanningproteomicsrepresentation_learning+3

    A sequence-based learning-to-rank variant effect predictor that aligns and aggregates ~1,100 overlapping deep mutational scanning assays into an assay-agnostic measure of mutational tolerance.

    Protein
    10Openness
  • resLens

    1
    George Washington UniversityFebruary 16, 2026antibiotic_resistance_gene_detectiongenomicslanguage_model+4

    A family of genomic language models fine-tuned from a pretrained DNA language model to detect and classify antibiotic resistance genes beyond reference-database limits.

    DNA & Gene
    11Openness