All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 118 filtered models
UltraNMR
11—Hong Kong University of Science and Technology +4 othersJune 18, 2026foundation_modelself_supervisedtransfer_learning+1NMR foundation model trained on 158 million simulated 1H and 13C spectra, transferring simulation-learned representations to real experimental data.
Small moleculeMetabolomics43OpennessGENATATOR
——23Ab initio gene annotation model that predicts gene boundaries and exon-intron structure from raw DNA, generalizing zero-shot to unseen species.
DNA & GeneRNA22OpennessCREP
———Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.
DNA & Gene8OpennessCellpin
———Variational autoencoder trained on scRNA-seq and applied frozen to impute unmeasured genes and denoise spatial transcriptomics profiles.
Spatial omicsSingle-cell22OpennessBrainGFM
173—Graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero-shot disorder classification.
Biosignals16OpennessCryoProt
———Protein representation learning from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.
ImagingProtein11OpennessDanioDecima
———Zebrafish sequence-to-function model predicting cell-type-specific gene expression from DNA sequence across embryonic development.
DNA & GeneSingle-cell22OpennessFlowTransOP
———Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.
Single-cell87Openness- Hong Kong University of Science and Technology +9 othersMay 25, 2026foundation_modelself_supervisedtransfer_learning+2
Lung pathology foundation model adapted from Virchow2 on whole-slide images, validated across 32 tasks spanning the lung diagnostic workflow.
Pathology5Openness ProtmRNA
2——Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.
RNA11OpennessDamageFormer
1——Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.
DNA & Gene45OpennessDomain-specific foundation model for zero-shot plant root image segmentation, built on a MobileSAM backbone and trained across nine root datasets.
Imaging74OpennessSpaRank
———Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.
Spatial omics8OpennessConvergeCELL
——34Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.
Single-cell67Opennesssm_protgpt2
——7Three fixed ProtGPT2 fine-tunes specialized for metalloprotein generation, trained on ProteinMPNN-derived synthetic sequences.
Protein38OpennessCoMole
———Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.
Small molecule23OpennessHyperMap
—1—Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.
Single-cell11OpennessAF2Dock
151—Protein-protein docking model adapting AlphaFold-Multimer with a docking module and flow-matching training to assemble subunits without MSAs.
Protein77OpennessDeep-Plant
1——Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.
DNA & Gene87Opennessmuat
8——Transformer that classifies tumour types and subtypes from somatic variants in whole-genome and whole-exome data, with auto-downloading checkpoints.
DNA & Gene65OpennessEEG foundation model pretrained by spectrogram reconstruction that improves online directional motor-imagery brain-computer interface control.
Biosignals18OpennessZeroFold
———University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.
RNAProtein23OpennessCLIPepPI
2——Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.
Protein50OpennessHERCULES
———Protein language model that classifies RNA-binding proteins, localizes RNA-binding domains, and scores mutation effects at single-residue resolution.
Protein44Openness