All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 31 filtered models
Vermeer
2——Channel-adaptive autoregressive generative model that synthesizes in-silico fluorescence microscopy of protein subcellular localization from amino-acid sequence and cellular landmark stains.
ImagingProtein17OpennessmnDINO
———A DINO-pretrained vision transformer for accurate, robust segmentation of micronuclei in DNA-stained fluorescence microscopy across cell lines and instruments.
Imaging32OpennessPerturbGen
21——Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cellular trajectories over time.
Single-cell72OpennessCellPace
———A temporal diffusion-forcing generative framework for simulating, interpolating, and forecasting single-cell developmental dynamics from irregularly sampled time-series data.
Single-cell9OpennessCLM-X
———Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6A multimodal single-cell foundation model with a multiway Transformer that jointly models scRNA-seq and scATAC-seq, including RNA-only, ATAC-only, and paired inputs.
Single-cell4OpennessA hierarchical sequence-based protein representation that encodes proteins as discrete 'words' for zero-shot functional discovery and generative design.
Protein24OpennessOKR-CELL
———Cross-modal cell-language foundation model that aligns single-cell expression with LLM-enriched textual descriptions using a noise-robust contrastive objective.
Single-cellLanguage model23OpennessA multimodal architecture that couples pretrained DNA, RNA, and protein language models via directional cross-attention following the central dogma to form a unified Virtual Cell Embedding.
DNA & GeneRNAProtein22OpennessSpatialDINO
—1—A native 3D vision transformer self-supervised on unlabeled fluorescence microscopy volumes that generalizes to unseen object classes without retraining or voxel annotations.
Imaging8OpennessscMOBA
———Chinese Academy of Sciences +1 otherDecember 2, 2025cell_biologycell_type_annotationdata_integration+6A conversational single-cell and spatial multi-omics brain agent pretrained on 130 million cells across species for zero-shot cell annotation and disease prediction.
Single-cellLanguage model5OpennessMicellangelo
———Eindhoven University of TechnologyNovember 24, 2025cell_biologycell_morphology_simulationconditional_generation+5Flow-matching generative model that simulates high-resolution fluorescence images of human fibroblasts conditioned on surface micro-topographies, a digital twin of cell-material interactions.
Imaging5OpennessscLDM
525—A scalable latent diffusion model for generating realistic single-cell gene expression profiles, using a permutation-invariant VAE and flow-matching diffusion transformer.
Single-cell75OpennessscLDM.CD4
7—9A fine-tuned scLDM variant trained on 14.5 million CD4+ T cells for counterfactual prediction of single-gene perturbation effects in immune cells.
Single-cell75OpennessrBio
14213—Chan Zuckerberg InitiativeAugust 18, 2025biological_question_answeringcell_biologyfoundation_model+4A reasoning language model post-trained on virtual cell simulations to answer complex biological questions about gene perturbations in natural language.
Language model60OpennessCellpose-SAM
2.2K152—Generalist cell segmentation model combining SAM's ViT-L backbone with Cellpose flow fields. First model to surpass average human annotators on the Cellpose benchmark.
Imaging50OpennessCellpose 3
2.2K322—Generalist cell segmentation framework with a super-generalist cyto3 model and one-click image restoration networks optimized for downstream segmentation quality.
Imaging65OpennessSubCell
610—Chan Zuckerberg Initiative +2 othersDecember 8, 2024cell_biologyfluorescence_microscopyfoundation_model+4Self-supervised Vision Transformer models trained on proteome-wide fluorescence microscopy images from the Human Protein Atlas for subcellular protein localization.
Imaging84OpennessCELL-Diff
5——A unified diffusion model enabling bidirectional transformation between protein amino acid sequences and fluorescence microscopy images for subcellular localization prediction.
Imaging87OpennessDynaCLR
972—A self-supervised contrastive learning method for embedding cell and organelle dynamics from time-lapse microscopy using temporal regularization and single-cell tracking.
Imaging71OpennessCellFM
10864—An 800M-parameter single-cell foundation model pre-trained on 100 million human cells via a RetNet architecture for cell annotation, perturbation prediction, and gene analysis.
Single-cell26OpennessCytoland
979—A suite of virtual staining models that translate label-free microscopy images into fluorescent-equivalent staining of nuclei and plasma membranes.
Imaging99Openness