All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 112 of 12 filtered models

  • Cellpin

    Technical University of MunichJune 5, 2026denoisinggene_imputationsingle_cell+4

    A VAE trained on scRNA-seq reference data and applied frozen at inference to impute unmeasured genes and denoise spatial transcriptomics profiles.

    Spatial omicsSingle-cell
    22Openness
  • Chreode

    University of North Carolina at Chapel Hill +2 othersMay 27, 2026cell_fate_predictioncrispr_perturbationdevelopmental_trajectory_modeling+8

    A cell world model pretrained on a 2.4M-cell mouse embryonic atlas that predicts one-step transcriptional state transitions and transfers to perturbation prediction.

    Single-cell
    26Openness
  • RegVelo

    1538
    Helmholtz MunichMay 11, 2026cell_fate_mappingchromatingene_regulatory_network_inference+6

    Bayesian deep generative model that integrates gene regulatory networks into RNA velocity inference, enabling cell fate mapping and in silico perturbation of transcription factors.

    Single-cell
    59Openness
  • AnewOmni

    721
    Tsinghua University +1 otherMarch 15, 2026antibodyde_novo_designdiffusion+6

    All-atom generative foundation model trained on 5M+ biomolecular complexes that designs small molecules, peptides, and nanobodies against a target site from one checkpoint.

    ProteinSmall molecule
    63Openness
  • PLUM

    1
    Iowa State UniversityFebruary 21, 2026antimicrobial_peptidesde_novo_designgenerative+3

    A conditional variational autoencoder for controlled antimicrobial peptide design that disentangles sequence, function, and length in its latent space.

    Protein
    56Openness
  • CryoLens

    16
    Chan Zuckerberg InitiativeJanuary 1, 2025cnncryo_etgenerative+6

    A variational autoencoder for interpretable 3D reconstruction and representation learning of protein subtomograms from cryo-ET data, trained on 5.8 million synthetic particles.

    Imaging
    74Openness
  • Chan Zuckerberg InitiativeJuly 1, 2024autoencodercell_type_annotationde_novo_design+6

    A variational autoencoder pretrained on 74 million human single-cell transcriptomes from the CELLxGENE Census for scalable batch correction, cell typing, and data integration.

    Single-cell
    96Openness
  • Zhang LabJanuary 30, 2024batch_correctiongene_expressionperturbation+2

    Disentangled VAE framework for joint batch correction, condition-key-gene detection, and perturbation prediction in multi-batch multi-condition scRNA-seq data.

    Single-cell
    79Openness
  • RfamGen

    4256
    Kyoto University +1 otherJanuary 1, 2024foundation_modelsequence_designvariational_autoencoder

    A VAE-based generative model that designs novel functional RNA sequences by encoding MSA and consensus secondary structure constraints from Rfam families.

    RNA
    10Openness
  • DPI

    356
    Xiamen UniversityJanuary 19, 2023cite_seqdata_integrationmultimodal+1

    End-to-end single-cell multimodal analysis framework using deep parametric inference to integrate RNA and protein data into a unified latent space.

    Single-cell
    45Openness
  • scVAE

    89
    Technical University of Denmark +1 otherAugust 15, 2020autoencodergene_expressionvariational_autoencoder

    Variational autoencoder for single-cell RNA-seq that models raw count distributions directly, producing latent cell representations without normalization preprocessing.

    Single-cell
    53Openness
  • scGen

    348617
    Theis LabJuly 29, 2019batch_correctiongenerativeout_of_distribution_generalization+4

    Variational autoencoder that predicts single-cell perturbation responses across cell types and species using latent space vector arithmetic.

    Single-cell
    43Openness