All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 118 filtered models

  • PlantGeneAnn

    12126
    Huazhong Agricultural UniversityJune 25, 2026dnafoundation_modelgene_structure_annotation+7

    Plant genome foundation model for ab initio gene structure annotation, predicting genes, coding sequences, and exons at single-nucleotide resolution.

    DNA & Gene
    66Openness
  • Omnii

    Radical NumericsJune 15, 2026convolutionaldnafoundation_model+6

    Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.

    DNA & Gene
    5Openness
  • CREP

    University of OxfordJune 7, 2026cis_regulatory_element_annotationdnaregulatory_genomics+4

    Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.

    DNA & Gene
    8Openness
  • MethylSeqNet

    University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6

    Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.

    DNA & Gene
    18Openness
  • ReCLIP

    University of Chicago +2 othersJune 4, 2026multi_taskprotein_protein_interaction_predictionproteomics+4

    Transformer that predicts protein-protein interactions at residue resolution, spanning mutations, PTMs, peptide-MHC binding, and disease variants.

    Protein
    22Openness
  • LDARNet

    41
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    Genomic foundation model with 120M parameters that learns adaptive DNA token boundaries by dynamic chunking, not fixed k-mer or byte-pair tokens.

    DNA & Gene
    26Openness
  • TESSERA

    5
    Weill Cornell MedicineJune 1, 2026cancer_genomicscell_type_annotationcontrastive_learning+5

    Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.

    DNA & Gene
    28Openness
  • DanioDecima

    Biohub +1 otherMay 29, 2026cnnde_novo_designdna+7

    Zebrafish sequence-to-function model predicting cell-type-specific gene expression from DNA sequence across embryonic development.

    DNA & GeneSingle-cell
    22Openness
  • ESMC

    2.9K102.1M
    BiohubMay 27, 2026foundation_modelmasked_language_modelingprotein_design+6

    Protein language model trained on roughly 2.8 billion sequences, forming the representation core of Biohub's world model of protein biology.

    Protein
    63Openness
  • D2D

    1
    Vrije Universiteit Brussel +1 otherMay 22, 2026binding_region_predictionepistasisintrinsically_disordered_regions+5

    Variant effect predictor pairing a protein language model with family-specific evolutionary constraints to score stability, binding, and epistasis.

    Protein
    29Openness
  • Genos-m

    26123
    BGI-HangzhouAIMay 21, 2026foundation_modelgene_fitness_predictionmetagenomics+7

    Mixture-of-Experts genomic foundation model for the human microbiome, with 4.7B parameters pretrained on bacterial, archaeal, and phage genomes.

    DNA & Gene
    73Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.

    RNA
    11Openness
  • University of FloridaMay 18, 2026bertbilstmcnn+11

    Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.

    DNA & Gene
    45Openness
  • Bio-BLIP

    Stanford UniversityMay 15, 2026foundation_modelgenomicsmendelian_disease+7

    Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.

    DNA & GeneLanguage model
    23Openness
  • PLM-SAE

    Shanghai Smart Logic Technology Co., Ltd.May 15, 2026autoencoderproteomicsrepresentation_learning+3

    Sparse autoencoders trained on protein language model embeddings to expose interpretable features and drive zero-shot variant effect prediction.

    Protein
    22Openness
  • ENSEMBITS

    7
    Vanderbilt UniversityMay 13, 2026function_predictionmolecular_dynamicsprotein_dynamics+5

    Protein conformational ensemble tokenizer that learns a discrete alphabet of states from molecular dynamics, reusable as a frozen feature layer.

    Protein
    66Openness
  • OmniGene-4

    1
    Huazhong University of Science and TechnologyMay 12, 2026dnafoundation_modelinstruction_following+7

    Unified bio-language Mixture-of-Experts model spanning DNA, protein sequence and structure, and biological text across eight task families.

    Language modelDNA & GeneProtein
    7Openness
  • ProtSent

    712
    Hebrew University of Jerusalem +1 otherMay 7, 2026contrastive_learningembeddingsproteomics+4

    Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.

    Protein
    87Openness
  • Wisteria

    Inner Mongolia UniversityMay 7, 2026cnndnafoundation_model+6

    DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier attention to capture multi-scale regulatory patterns.

    DNA & Gene
    10Openness
  • University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6

    Protein language model aligning ESM sequence embeddings with molecular dynamics trajectories for zero-shot mutation effect and stability prediction.

    Protein
    10Openness
  • Carbon

    2006.4K
    Hugging Face +2 othersMay 1, 2026dnafoundation_modelgenerative+3

    Autoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.

    DNA & Gene
    93Openness
  • MIMIC

    37
    Polymathic AIApril 27, 2026foundation_modelgenerativegenomics+6

    Generative multimodal foundation model spanning DNA, RNA, and protein, with any-to-any inference across genome, transcriptome, and proteome.

    RNAProteinDNA & Gene
    16Openness
  • CellPulse

    Wuhan Institute of VirologyApril 24, 2026drug_discoveryfoundation_modelgene_expression+5

    Direction-aware foundation model trained on bulk RNA-seq differential-expression profiles to simulate coordinated gene dynamics in viral infection.

    Single-cellLanguage model
    4Openness
  • Mach-1

    34
    Broad InstituteApril 21, 2026foundation_modelisoform_abundance_predictionpre_mrna+8

    Long-context RNA foundation model that predicts splicing, isoform abundance, and variant effects from 64 kb of unspliced pre-mRNA sequence.

    RNA
    39Openness