All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–14 of 14 filtered models
BoltzMol-1
4.1K——Small-molecule hit-discovery pipeline using Boltz-2 co-folding and affinity prediction to rank in-stock compounds or make-on-demand chemical space.
Small moleculeProtein7OpennessCoMole
———Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.
Small molecule23OpennessGPT-Rosalind
4.7K——OpenAI's frontier reasoning model for life-sciences research, tuned for multi-step workflows in protein engineering, genomics, and drug discovery.
Language model5OpennessDISCO
2103—Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.
Protein70OpennessMultiPUFFIN
———Multimodal foundation model pretrained on ~500K unlabeled PubChem molecules that jointly predicts nine thermophysical properties of small molecules.
Small molecule10OpennessMolX
—1—Monash UniversityMarch 1, 2026antibody_drug_conjugate_designbinding_affinity_predictiondrug_discovery+10Graph-transformer foundation model pretrained on 3M protein pockets and 5M molecules as E(3)-equivariant graphs for protein-ligand representation.
Protein11OpennessIsoDDE
———Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.
Protein13OpennessRFdiffusion3
90965—All-atom protein design diffusion model conditioned on ligands, nucleic acids, and other non-protein atoms, supporting enzyme and DNA binder design.
Protein80OpennessMAMMAL
11891KMulti-modal, multi-task biological foundation model trained on 2 billion samples spanning proteins, small molecules, and single-cell gene expression.
ProteinSmall moleculeSingle-cell74OpennessBioMed Multi-View
4675.2KMolecular foundation model that late-fuses graph, image, and SMILES encoders into one embedding for molecular property and drug target prediction.
Small molecule77OpennessBioT5+
127—415Text-to-text biological language model spanning molecules, proteins, and text, adding IUPAC names and multi-task instruction tuning to BioT5.
Language modelSmall moleculeProtein85OpennessRoseTTAFold All-Atom
815936—Deep network that predicts structures of full biological assemblies: proteins, nucleic acids, small molecules, metals, and covalent modifications.
Protein54OpennessBioT5
127—191Encoder-decoder framework unifying molecules, proteins, and natural language with SELFIES notation for cross-modal drug discovery tasks.
Language modelSmall moleculeProtein74OpennessMoLFormer-XL
406595209.9KLarge-scale chemical language model trained on 1.1 billion SMILES strings using linear attention transformers for molecular property prediction.
Small molecule86Openness