All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–23 of 23 filtered models
CREP
———Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.
DNA & Gene8OpennessC3P
1——Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.
DNA & Gene77OpennessDiscrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.
DNA & Gene49OpennessevoRate
———Genome language model that adds evolutionary-rate prediction to pretraining, improving representations for variant effect and regulatory genomics.
DNA & Gene14OpennessPuget
———Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.
DNA & Gene8OpennessNyxBind
1—2Hong Kong University of Science and TechnologyOctober 21, 2025bertbinding_site_predictioncontrastive_learning+5Transcription factor binding site prediction model that refines a DNABERT-2 backbone with contrastive learning across diverse TFBS types.
DNA & Gene40OpennessFlashRNA
182—Efficient sequence-to-function transformer for regulatory genomics, matching Borzoi-class models while training in about a day on a single GPU.
DNA & GeneRNA59OpennessAlphaGenome
2K154—DNA foundation model that predicts thousands of functional genomic tracks, from expression and splicing to chromatin, at single base-pair resolution.
DNA & Gene49OpennessseqLens
7——Genomic language models with disentangled attention, pretrained on prokaryotic and eukaryotic genomes for sequence classification and variant effects.
DNA & Gene18OpennessBorzoi
256256—Regulatory genomics model predicting cell-type-specific RNA-seq coverage from DNA sequence, unifying transcription, splicing, and polyadenylation.
DNA & Gene92OpennessGeneCompass
119137—Knowledge-informed cross-species foundation model pre-trained on 101 million human and mouse single-cell transcriptomes to decipher gene regulation.
Single-cell32OpennessPuffin
10655—Interpretable model of human transcription initiation that decomposes promoter activity into a minimal set of sequence rules at base-pair resolution.
DNA & Gene23OpennessgLM
9193—Genomic language model trained on metagenomic scaffolds that learns protein co-regulation and function by modeling gene context and operon structure.
DNA & Gene30OpennessEpiGePT
3311—Transformer model predicting context-specific epigenomic signals across cell types using DNA sequence and transcription factor activity profiles.
DNA & Gene65OpennessSpecies-Aware DNA Language Model
18538.1KMasked DNA language model trained on 800+ species with explicit species conditioning, separating conserved regulatory motifs from background bias.
DNA & Gene92OpennessSpecies-Aware DNA LM
29538.1KMasked DNA language model trained on over 800 vertebrate genomes and conditioned on species identity to learn conserved regulatory sequence features.
DNA & Gene76OpennessGeneBERT
—27—Multi-modal self-supervised transformer for regulatory genomics, pre-trained on DNA sequence together with transcription factor binding matrices.
DNA & Gene18OpennessEnformer
15.1K1.2K—Transformer that predicts gene expression and epigenomic signals from 200kb of DNA sequence, capturing distal enhancers up to 100kb from a promoter.
DNA & Gene84OpennessBasenji2
473225—Cross-species convolutional network trained jointly on human and mouse genomes to predict regulatory sequence activity and noncoding variant effects.
DNA & Gene79OpennessBig Bird
6333K341.8KSparse attention transformer that extends BERT to 8x longer sequences via random, local, and global attention, with genomic sequence applications.
DNA & Gene49OpennessBasenji
473515—Dilated convolutional network that predicts cell-type-specific epigenetic and transcriptional profiles from DNA sequence across mammalian genomes.
DNA & Gene73OpennessBasset
268955—Convolutional neural network that predicts DNA accessibility from sequence across 164 DNase-seq cell types, enabling variant effect prediction.
DNA & Gene80Openness