All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 123 of 23 filtered models

  • CREP

    University of OxfordJune 7, 2026cis_regulatory_element_annotationdnaregulatory_genomics+4

    Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.

    DNA & Gene
    8Openness
  • C3P

    1
    University of TorontoMay 24, 2026bacterial_genomeco_regulated_gene_retrievalcontrastive_learning+8

    Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.

    DNA & Gene
    77Openness
  • Cold Spring Harbor LaboratoryApril 1, 2026de_novo_designdiffusiongene_expression+5

    Discrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.

    DNA & Gene
    49Openness
  • evoRate

    University of TorontoFebruary 2, 2026genomicsmolecular_evolutionregulatory_genomics+4

    Genome language model that adds evolutionary-rate prediction to pretraining, improving representations for variant effect and regulatory genomics.

    DNA & Gene
    14Openness
  • Puget

    University of WashingtonNovember 20, 2025chromatindnafoundation_model+6

    Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.

    DNA & Gene
    8Openness
  • Nona

    3
    GenentechNovember 6, 2025discrete_diffusionfoundation_modelfunctional_genomics+8

    Genomics foundation model that unifies sequence-to-function prediction, DNA language modeling, and generative regulatory design in one backbone.

    DNA & GeneRNA
    8Openness
  • NyxBind

    12
    Hong Kong University of Science and TechnologyOctober 21, 2025bertbinding_site_predictioncontrastive_learning+5

    Transcription factor binding site prediction model that refines a DNABERT-2 backbone with contrastive learning across diverse TFBS types.

    DNA & Gene
    40Openness
  • FlashRNA

    182
    Deep GenomicsOctober 15, 2025foundation_modelgene_expressiongenomics+4

    Efficient sequence-to-function transformer for regulatory genomics, matching Borzoi-class models while training in about a day on a single GPU.

    DNA & GeneRNA
    59Openness
  • AlphaGenome

    2K154
    Google DeepMindJune 27, 2025chromatinfoundation_modelgene_expression+4

    DNA foundation model that predicts thousands of functional genomic tracks, from expression and splicing to chromatin, at single base-pair resolution.

    DNA & Gene
    49Openness
  • seqLens

    7
    George Washington UniversityMarch 12, 2025bertfoundation_modelgenomics+7

    Genomic language models with disentangled attention, pretrained on prokaryotic and eukaryotic genomes for sequence classification and variant effects.

    DNA & Gene
    18Openness
  • Borzoi

    256256
    Calico Life SciencesJanuary 9, 2025cnngene_expressionregulatory_genomics+5

    Regulatory genomics model predicting cell-type-specific RNA-seq coverage from DNA sequence, unifying transcription, splicing, and polyadenylation.

    DNA & Gene
    92Openness
  • GeneCompass

    119137
    Chinese Academy of SciencesOctober 8, 2024cross_speciesfoundation_modelregulatory_genomics+1

    Knowledge-informed cross-species foundation model pre-trained on 101 million human and mouse single-cell transcriptomes to decipher gene regulation.

    Single-cell
    32Openness
  • Puffin

    10655
    UT Southwestern Medical CenterApril 26, 2024chromatincnngene_expression+3

    Interpretable model of human transcription initiation that decomposes promoter activity into a minimal set of sequence rules at base-pair resolution.

    DNA & Gene
    23Openness
  • gLM

    9193
    Harvard University +1 otherApril 3, 2024foundation_modelgenomicsmetagenomics+2

    Genomic language model trained on metagenomic scaffolds that learns protein co-regulation and function by modeling gene context and operon structure.

    DNA & Gene
    30Openness
  • EpiGePT

    3311
    Tsinghua UniversityJuly 18, 2023chromatinepigenomicsfoundation_model+2

    Transformer model predicting context-specific epigenomic signals across cell types using DNA sequence and transcription factor activity profiles.

    DNA & Gene
    65Openness
  • Technical University of MunichJanuary 27, 2023cross_speciesfoundation_modelregulatory_genomics

    Masked DNA language model trained on 800+ species with explicit species conditioning, separating conserved regulatory motifs from background bias.

    DNA & Gene
    92Openness
  • Technical University of MunichJanuary 27, 2023bertdnafoundation_model+6

    Masked DNA language model trained on over 800 vertebrate genomes and conditioned on species identity to learn conserved regulatory sequence features.

    DNA & Gene
    76Openness
  • GeneBERT

    27
    Carnegie Mellon UniversityOctober 11, 2021bertchromatinfoundation_model+6

    Multi-modal self-supervised transformer for regulatory genomics, pre-trained on DNA sequence together with transcription factor binding matrices.

    DNA & Gene
    18Openness
  • Enformer

    15.1K1.2K
    Google DeepMindOctober 4, 2021dnafoundation_modelgene_expression+2

    Transformer that predicts gene expression and epigenomic signals from 200kb of DNA sequence, capturing distal enhancers up to 100kb from a promoter.

    DNA & Gene
    84Openness
  • Basenji2

    473225
    Calico Life SciencesAugust 6, 2020chromatincnngene_expression+5

    Cross-species convolutional network trained jointly on human and mouse genomes to predict regulatory sequence activity and noncoding variant effects.

    DNA & Gene
    79Openness
  • Big Bird

    6333K341.8K
    Google ResearchJuly 28, 2020dnafoundation_modelgenomics+4

    Sparse attention transformer that extends BERT to 8x longer sequences via random, local, and global attention, with genomic sequence applications.

    DNA & Gene
    49Openness
  • Basenji

    473515
    Calico Life SciencesMay 1, 2018chromatincnngene_expression+4

    Dilated convolutional network that predicts cell-type-specific epigenetic and transcriptional profiles from DNA sequence across mammalian genomes.

    DNA & Gene
    73Openness
  • Basset

    268955
    Harvard UniversityJuly 1, 2016chromatincnngenomics+3

    Convolutional neural network that predicts DNA accessibility from sequence across 164 DNase-seq cell types, enabling variant effect prediction.

    DNA & Gene
    80Openness