All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 27 filtered models

  • ReCLIP

    University of Chicago +2 othersJune 4, 2026multi_taskpeptide_mhc_binding_predictionprotein_protein_interaction_prediction+5

    Transformer framework that models protein-protein interactions at residue resolution, generalizing zero-shot to unseen MHC alleles and sequence-neutral PTMs from one fixed checkpoint.

    Protein
    22Openness
  • University of Texas at Austin +1 otherApril 17, 2026bertdrug_discoveryfoundation_model+7

    SMILES-based chemical language models pretrained on 100M+ molecules to natively represent therapeutic peptide chemistry, including non-canonical residues.

    Small moleculeProtein
    79Openness
  • EnzyGen2

    30
    Carnegie Mellon UniversityMarch 31, 2026de_novo_designenzyme_designfoundation_model+5

    A 730M-parameter protein foundation model that co-designs enzyme sequence and 3D structure under small-molecule ligand guidance for de novo enzyme design.

    ProteinSmall molecule
    89Openness
  • HERCULES

    Italian Institute of TechnologyMarch 17, 2026multi_taskproteomicsrna_binding_prediction+4

    Protein language model that predicts RNA-binding domains, global RNA-binding propensity, and mutation effects at single-residue resolution from sequence.

    Protein
    44Openness
  • Pengcheng Laboratory +2 othersMarch 13, 2026chain_of_thoughtcheminformaticsdrug_discovery+6

    A DeepSeek-7B-based multi-task large reasoning model that applies chain-of-thought reasoning and reinforcement learning across ~10 molecular science task families.

    Small moleculeLanguage model
    21Openness
  • University of Texas at Arlington +1 otherMarch 13, 2026gangenerativehistology+4

    Foundation-model-guided virtual staining that generates four IHC markers (HER2, Ki67, ER, PR) from H&E using a single SPADE-UNet conditioned on a frozen UNI encoder.

    Pathology
    17Openness
  • Liquid AI +1 otherMarch 3, 2026admet_predictiondrug_discoverydrug_target_activity_prediction+6

    A 2.6B-parameter Liquid Foundation Model fine-tuned via Insilico's MMAI Gym to handle ADMET, retrosynthesis, drug-target activity, and molecular optimization in one checkpoint.

    Small moleculeLanguage model
    7Openness
  • MultiPUFFIN

    NTNU +2 othersMarch 1, 2026drug_discoveryfoundation_modelgraph_neural_network+6

    A multimodal, domain-constrained foundation model that self-supervises on ~500K PubChem molecules to jointly predict nine thermophysical properties of small molecules.

    Small molecule
    10Openness
  • ChIANet

    Central South UniversityFebruary 25, 20263d_genomechromatinchromatin_contact_prediction+4

    Multimodal deep learning model that predicts protein-mediated chromatin contact maps and loops de novo from protein-binding profiles and sequence across cell types.

    DNA & Gene
    10Openness
  • MAGNET

    Huazhong University of Science and TechnologyDecember 25, 2025denoisingfluorescence_microscopyfoundation_model+7

    An all-in-one foundation model for microscopic image restoration, unifying 8 tasks across 5 microscopy modalities and 2D/3D data, with zero-shot inference on unseen imaging systems.

    Imaging
    7Openness
  • OMTRA

    University of Pittsburgh +1 otherDecember 4, 2025conformer_generationde_novo_designdrug_discovery+8

    A pretrained multi-task flow-matching model for structure-based drug design, unifying de novo design, docking, conformer generation, and pharmacophore conditioning.

    Small moleculeProtein
    72Openness
  • University of North Carolina at Chapel HillOctober 21, 2025behavior_predictionbrain_connectomedisease_diagnosis+6

    A 1.2B-parameter fMRI foundation model of brain connectomes that uses brain-environment interaction tokens and multitask learning for behavior and disease prediction.

    Biosignals
    26Openness
  • Shanghai Jiao Tong UniversityOctober 1, 2025brain_age_predictionbrain_mridensenet+8

    A self-supervised foundation model for structural brain MRI combining DenseNet and Vision Transformer with Mixture of Experts for multi-task brain disease diagnosis and brain age prediction.

    Imaging
    8Openness
  • BrainFM

    176
    Johns Hopkins University +4 othersAugust 30, 2025foundation_modelimage_synthesismulti_task+4

    A modality-agnostic, multi-task foundation model for human brain imaging that runs five core tasks across uncalibrated CT and MRI without retraining.

    Imaging
    75Openness
  • Rensselaer Polytechnic Institute +2 othersFebruary 11, 2025chest_ctdisease_classificationfoundation_model+7

    Multimodal multitask foundation model that fuses 3D low-dose chest CT with clinical data to perform 17 lung-cancer-screening tasks via free-text question answering.

    Imaging
    71Openness
  • MedPLIB

    130337
    Baidu +3 othersDecember 12, 2024histologymedical_image_groundingmixture_of_experts+8

    Biomedical multimodal LLM with pixel-level insight, combining visual question answering, pixel-grounded prompts, and segmentation via a mixture-of-experts design.

    ImagingLanguage model
    80Openness
  • MAMMAL

    11081.8K
    IBM ResearchOctober 28, 2024cell_type_annotationdrug_discoveryfoundation_model+7

    Multi-modal, multi-task biological foundation model trained on 2 billion samples spanning proteins, small molecules, and single-cell gene expression.

    ProteinSmall moleculeSingle-cell
    74Openness
  • gCIS

    107
    United Imaging Intelligence +1 otherOctober 14, 2024ct_imagingfoundation_modellesion_detection+4

    A general CT image segmentation foundation model that uses task-prompted automatic pathway decoding to segment 83 anatomical structures and lesions across whole-body CT.

    Imaging
    14Openness
  • BELT-2

    12
    University of Technology SydneyAugust 28, 2024brain_to_textconformercontrastive_learning+6

    EEG-to-language multi-task foundation model that pairs a Q-Conformer encoder with frozen LLMs to decode coherent sentences from non-invasive brain signals.

    BiosignalsLanguage model
    30Openness
  • MuBind

    271
    Theis LabAugust 8, 2024chromatincnndna+7

    Deep learning model predicting single-cell read counts from DNA sequence features and cell transition graphs to identify transcriptional regulators.

    Single-cell
    59Openness
  • BiomedGPT

    709373
    Lehigh University +9 othersAugust 7, 2024foundation_modelhistologyimage_captioning+7

    Open-source, lightweight generalist vision-language foundation model for diverse biomedical imaging and text tasks.

    Language modelImagingPathology
    33Openness
  • Prot2Token

    3810
    University of MissouriJune 3, 2024foundation_modelmulti_taskprotein_function_prediction+1

    A unified multi-task framework that converts diverse protein prediction tasks into autoregressive next-token prediction using pre-trained protein language model encoders.

    Protein
    13Openness
  • University of OxfordMarch 18, 2024accelerometrycnnhuman_activity_recognition+5

    Self-supervised CNN pretrained on 700,000 person-days of UK Biobank accelerometer data for human activity recognition, transferable across devices and cohorts.

    Biosignals
    28Openness
  • ProLLaMA

    207871.2K
    PKU-YuanGroupFebruary 26, 2024foundation_modellanguage_modelllama+1

    A 7B-parameter protein language model built on LLaMA-2 that performs both protein sequence generation and superfamily classification in a unified framework.

    Protein
    95Openness