All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Applications

Architectures

Learning Paradigms

Biological Subjects

Showing 19 of 9 filtered models

Protein

LigandMPNN

Institute for Protein Design

Protein sequence design method that explicitly models small molecules, nucleotides, and metals at atomic resolution, enabling ligand-aware design with 100+ validated designs.

567183
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Single-cell

PINNACLE

Harvard University

Geometric deep learning model generating context-aware protein representations across 156 cell-type contexts from a multi-organ single-cell atlas.

10160
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Single-cell

scPML

Shenzhen University

Pathway-based multi-view learning for cell type annotation from single-cell RNA-seq data, integrating biological pathway knowledge through graph neural networks.

1211
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Protein

ProteinShake

BorgwardtLab

Python framework for building standardized protein structure datasets and benchmarks, with pre-processed data from PDB and AlphaFoldDB for deep learning evaluation.

114
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Protein

Chroma

Generate:Biomedicines

Generative diffusion model for programmable protein design that jointly samples novel structures and sequences, conditioned on symmetry, shape, and natural language.

812
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Protein

ABGNN

Huazhong University of Science and Technology / Microsoft Research

Graph neural network framework for antigen-specific antibody CDR design, combining a pre-trained antibody language model with one-shot sequence and structure generation.

5525
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Protein

ESM-GearNet

Mila

A joint sequence-structure representation learning framework combining ESM-2 protein language model embeddings with GearNet geometric graph neural networks.

112
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Protein

GearNet

Mila / IBM Research

A geometric relational graph neural network that learns protein structure representations via geometry-aware message passing and self-supervised pretraining.

297
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Protein

ProteinMPNN

Institute for Protein Design

Message passing neural network for fixed-backbone protein sequence design. Achieves 52.4% native sequence recovery, far surpassing Rosetta's 32.9%.

1.7K1.6K
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