All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 32 filtered models
Tox21mer
———National Institute of Environmental Health SciencesJune 15, 2026embeddingsfoundation_modelrepresentation_learning+2Toxicity screening foundation model that encodes Tox21 concentration-response curves and assay metadata into reusable 768-dimensional embeddings.
Small moleculeBiosignals23OpennessProtSent
7—12Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.
Protein87OpennessGATSBI
13——Graph attention model that learns context-aware protein embeddings from protein-protein interaction, co-expression, and tissue association networks.
Protein94OpennessPost-hoc method that restores monotonic scaling to ESM-2 embeddings, yielding Matryoshka-style nested representations for variant effect prediction.
Protein58OpennessProtAlign
———Lawrence Livermore National LaboratoryMarch 6, 2026contrastive_learningcross_modal_retrievalembeddings+4Cross-modal protein encoder that aligns ESM-2 sequence embeddings with ProteinMPNN structure embeddings in a shared space for cross-modal retrieval.
Protein35OpennessEnzPlacer
———Enzyme function prediction model that uses contrastive learning to assign the first three EC digits to enzymes with functions unseen during training.
Protein59OpennessEVA
——89Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessTM-Vec 2
—1—Protein structural homology search from sequence alone, embedding proteins so that structural similarity becomes a fast nearest-neighbor lookup.
Protein4OpennessMetagenBERT
———Annotation-free metagenome embedding pipeline that encodes raw DNA reads with genomic language models and pools them via FAISS k-means clustering.
DNA & Gene22OpennessMicroGenomer
10——470M-parameter microbial genome foundation model trained on 234.5B base pairs for multi-scale genomic representation and trait prediction.
DNA & Gene44Opennessvir2vec
31388Pan-viral genomic language model producing fixed genome-level embeddings of viral DNA and RNA, reused across classification tasks without retraining.
DNA & Gene53OpennessH3BERTa
1—201Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.
ProteinLanguage model83OpennessStructure-based conformational B-cell epitope predictor that scores local antigen surface patches with ESM-2 embeddings and an ensemble MLP.
Protein12OpennessLSM-MS2
———Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.
MetabolomicsSmall molecule4OpennessSiamese protein language model whose embedding distances approximate TM-score and lDDT, enabling alignment-free protein structure comparison.
Protein5OpennessZebraformer
—1—Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.
Single-cell46OpennessMedSigLIP
29837421KMedically tuned SigLIP encoder from Google that maps medical images and text into one embedding space for zero-shot classification and retrieval.
ImagingPathology30OpennessFoldMatch
11——Protein structure embedding model that compresses each 3D fold into a single fixed-length vector for proteome-wide similarity search and clustering.
Protein23OpennessTahoe-100M-SCVI
1.7K123—scVI variational autoencoder trained on the Tahoe-100M drug-perturbation atlas, giving a 10-dimensional embedding of treated cancer cell states.
Single-cell93OpennessRIME
———RNA-RNA interaction prediction framework that scores pairing between long transcripts directly from sequence using Nucleotide Transformer embeddings.
RNA14OpennessSNPBag
15——Genomics foundation model for genome-scale SNP analysis, handling imputation, phasing, ancestry, and relatedness from one 0.8B-parameter checkpoint.
DNA & Gene29OpennessSFM-Protein
—3—Protein language model that captures short- and long-range residue co-evolution through a dual pre-training objective, at 3B parameters.
Protein10OpennessCXR Foundation
19982199Chest X-ray embedding model built on ELIXR, producing image and image-text embeddings for data-efficient and zero-shot radiograph classification.
ImagingDNABERT-S
1305324.1KDNA embedding model built on DNABERT-2, using contrastive learning to cluster sequences by species for metagenomic binning without labeled data.
DNA & Gene53Openness