All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 32 filtered models

  • Tox21mer

    National Institute of Environmental Health SciencesJune 15, 2026embeddingsfoundation_modelrepresentation_learning+2

    Toxicity screening foundation model that encodes Tox21 concentration-response curves and assay metadata into reusable 768-dimensional embeddings.

    Small moleculeBiosignals
    23Openness
  • ProtSent

    712
    Hebrew University of Jerusalem +1 otherMay 7, 2026contrastive_learningembeddingsproteomics+4

    Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.

    Protein
    87Openness
  • GATSBI

    13
    Stanford UniversityApril 3, 2026embeddingsfunction_predictiongraph_attention_network+4

    Graph attention model that learns context-aware protein embeddings from protein-protein interaction, co-expression, and tissue association networks.

    Protein
    94Openness
  • Duke UniversityMarch 8, 2026embeddingsknowledge_distillationproteomics+3

    Post-hoc method that restores monotonic scaling to ESM-2 embeddings, yielding Matryoshka-style nested representations for variant effect prediction.

    Protein
    58Openness
  • ProtAlign

    Lawrence Livermore National LaboratoryMarch 6, 2026contrastive_learningcross_modal_retrievalembeddings+4

    Cross-modal protein encoder that aligns ESM-2 sequence embeddings with ProteinMPNN structure embeddings in a shared space for cross-modal retrieval.

    Protein
    35Openness
  • EnzPlacer

    Iowa State UniversityFebruary 23, 2026contrastive_learningec_number_predictionembeddings+6

    Enzyme function prediction model that uses contrastive learning to assign the first three EC digits to enzymes with functions unseen during training.

    Protein
    59Openness
  • EVA

    89
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • TM-Vec 2

    1
    Arizona State UniversityFebruary 5, 2026embeddingshomology_detectionproteomics+3

    Protein structural homology search from sequence alone, embedding proteins so that structural similarity becomes a fast nearest-neighbor lookup.

    Protein
    4Openness
  • MetagenBERT

    MetagenBERT AuthorsJanuary 5, 2026bertdnaembeddings+5

    Annotation-free metagenome embedding pipeline that encodes raw DNA reads with genomic language models and pools them via FAISS k-means clustering.

    DNA & Gene
    22Openness
  • MicroGenomer

    10
    BGI ResearchDecember 29, 2025embeddingsfoundation_modelgenomics+6

    470M-parameter microbial genome foundation model trained on 234.5B base pairs for multi-scale genomic representation and trait prediction.

    DNA & Gene
    44Openness
  • vir2vec

    31388
    University of FloridaDecember 12, 2025embeddingsfoundation_modelgenomics+6

    Pan-viral genomic language model producing fixed genome-level embeddings of viral DNA and RNA, reused across classification tasks without retraining.

    DNA & Gene
    53Openness
  • H3BERTa

    1201
    University of BernNovember 3, 2025antibodyantibody_repertoire_analysisbert+8

    Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.

    ProteinLanguage model
    83Openness
  • Albert Einstein College of MedicineOctober 30, 2025antibodyantibody_designembeddings+5

    Structure-based conformational B-cell epitope predictor that scores local antigen surface patches with ESM-2 embeddings and an ensemble MLP.

    Protein
    12Openness
  • LSM-MS2

    Matterworks, Inc.October 30, 2025compound_annotationdisease_classificationembeddings+7

    Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.

    MetabolomicsSmall molecule
    4Openness
  • Harvard Medical SchoolOctober 27, 2025embeddingsrepresentation_learningsiamese_network+1

    Siamese protein language model whose embedding distances approximate TM-score and lDDT, enabling alignment-free protein structure comparison.

    Protein
    5Openness
  • MNCN-CSICJuly 9, 2025bertembeddingsfoundation_model+4

    Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.

    Single-cell
    46Openness
  • MedSigLIP

    29837421K
    Google Research +1 otherJuly 9, 2025contrastive_learningembeddingsfoundation_model+7

    Medically tuned SigLIP encoder from Google that maps medical images and text into one embedding space for zero-shot classification and retrieval.

    ImagingPathology
    30Openness
  • FoldMatch

    11
    RCSB Protein Data Bank +1 otherMarch 6, 2025embeddingsrepresentation_learningstructural_biology+2

    Protein structure embedding model that compresses each 3D fold into a single fixed-length vector for proteome-wide similarity search and clustering.

    Protein
    23Openness
  • Tahoe-100M-SCVI

    1.7K123
    Tahoe TherapeuticsFebruary 20, 2025autoencodercancerembeddings+6

    scVI variational autoencoder trained on the Tahoe-100M drug-perturbation atlas, giving a 10-dimensional embedding of treated cancer cell states.

    Single-cell
    93Openness
  • RIME

    Italian Institute of TechnologyFebruary 16, 2025embeddingsrnatransfer_learning+1

    RNA-RNA interaction prediction framework that scores pairing between long transcripts directly from sequence using Nucleotide Transformer embeddings.

    RNA
    14Openness
  • SNPBag

    15
    Zhejiang LabJanuary 29, 2025embeddingsfoundation_modelgenomics+3

    Genomics foundation model for genome-scale SNP analysis, handling imputation, phasing, ancestry, and relatedness from one 0.8B-parameter checkpoint.

    DNA & Gene
    29Openness
  • Microsoft ResearchOctober 31, 2024embeddingsfoundation_model

    Protein language model that captures short- and long-range residue co-evolution through a dual pre-training objective, at 3B parameters.

    Protein
    10Openness
  • Google ResearchAugust 2, 2024chest_radiographycnncontrastive_learning+9

    Chest X-ray embedding model built on ELIXR, producing image and image-text embeddings for data-efficient and zero-shot radiograph classification.

    Imaging
  • DNABERT-S

    1305324.1K
    MAGICS LabFebruary 13, 2024contrastive_learningdnaembeddings+3

    DNA embedding model built on DNABERT-2, using contrastive learning to cluster sequences by species for metagenomic binning without labeled data.

    DNA & Gene
    53Openness