All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 142 filtered models
LEAF-1
———Genomics foundation model that represents individual DNA fragments in a learned semantic space for cell-free DNA cancer detection and cell typing.
DNA & GeneSingle-cell4OpennessGAZE
———Physics-informed graph neural network predicting metabolite concentrations from gene expression, generalizing zero-shot to unseen metabolites.
MetabolomicsSmall moleculeDNA & Gene19OpennesseRNAformer
2——Enhancer RNA mapping model that locates eRNA loci genome-wide from DNA sequence and aggregated RNA-seq signal using a CNN-transformer architecture.
DNA & GeneRNA95OpennessPlantGeneAnn
12—126Plant genome foundation model for ab initio gene structure annotation, predicting genes, coding sequences, and exons at single-nucleotide resolution.
DNA & Gene66OpennessGENATATOR
——23Ab initio gene annotation model that predicts gene boundaries and exon-intron structure from raw DNA, generalizing zero-shot to unseen species.
DNA & GeneRNA22OpennessvBx-1.0
———Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.
Single-cellDNA & Gene5OpennessRepGene
———Gene representation framework fusing DNA, transcript, protein, text, and single-cell embeddings into one latent space that survives missing views.
DNA & GeneProteinSingle-cell22OpennessOmnii
———Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.
DNA & Gene5OpennessBetaInfer
———Technion – Israel Institute of Technology +2 othersJune 14, 2026generativegenomicsmolecular_evolution+4Generative transformer for phylogenetic inference that transduces sets of unaligned molecular sequences directly into Newick-format trees.
DNA & GeneProtein8OpennessDNAGPT2
———Family of ten compact GPT-2 decoder-only DNA language models spanning BPE vocabularies from 16 to 8192 tokens, built for lossless genome compression.
DNA & Gene52OpennessHoloCell
———860M-parameter generative single-cell foundation model that jointly represents and generates epigenomic, transcriptomic, and proteomic modalities.
Single-cellDNA & Gene21OpennessBacteReason
———University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5Reasoning LLM that predicts antimicrobial susceptibility of clinical bacterial isolates and supplies mechanistic explanations for each prediction.
DNA & GeneLanguage model20OpennessCREP
———Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.
DNA & Gene8OpennessMethylSeqNet
———University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.
DNA & Gene18Opennesstf-SFM
—2—Transcription factor-DNA binding specificity prediction from sequence, with a physics-derived dual-encoder trained by symmetric contrastive learning.
DNA & Gene18OpennesscrisprSFM
—2—CRISPR off-target prediction model that scores gRNA-DNA specificity from sequence, framing guide-target recognition as cross-modal retrieval.
DNA & Gene19OpennessLDARNet
41—Genomic foundation model with 120M parameters that learns adaptive DNA token boundaries by dynamic chunking, not fixed k-mer or byte-pair tokens.
DNA & Gene26OpennessTESSERA
5——Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.
DNA & Gene28OpennessDanioDecima
———Zebrafish sequence-to-function model predicting cell-type-specific gene expression from DNA sequence across embryonic development.
DNA & GeneSingle-cell22OpennessOryzaG3
———700M-parameter DNA language model pretrained on the rice pangenome, serving as a reusable base model for crop genomics and molecular breeding.
DNA & Gene19OpennessC3P
1——Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.
DNA & Gene77OpennessGenos-m
26—123Mixture-of-Experts genomic foundation model for the human microbiome, with 4.7B parameters pretrained on bacterial, archaeal, and phage genomes.
DNA & Gene73OpennessPlasmidLM
2——Promptable DNA language model that generates multi-kilobase plasmid sequences from plain-language component specs, refined with verifiable rewards.
DNA & Gene49Openness