All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 106 filtered models
CREP
———Fine-tuned Enformer derivative that predicts discrete, interpretable cis-regulatory element class annotations (enhancer, promoter, insulator) directly from DNA sequence across human cell types.
DNA & Gene8OpennessBacteReason
———University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5A reasoning LLM fine-tuned on clinical antimicrobial-susceptibility data augmented with mechanistic rationales, predicting susceptibility with explanations for novel isolate-antibiotic pairs.
DNA & GeneLanguage model20OpennessMethylSeqNet
———University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Conditions a pretrained DNA sequence embedding on CpG methylation to predict gene regulation across cell types and alleles, generalizing zero-shot to imprinting, X-inactivation, and accessibility.
DNA & Gene18Opennesstf-SFM
———Specificity Foundation Model that predicts transcription factor-DNA binding specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
DNA & Gene18OpennesscrisprSFM
———Specificity Foundation Model that predicts CRISPR gRNA off-target DNA specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
DNA & Gene19OpennessLDARNet
—1—A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.
DNA & Gene26OpennessTESSERA
5——Self-supervised foundation model that learns reusable representations of cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types.
DNA & Gene28OpennessDanioDecima
———A zebrafish DNA sequence-to-function model predicting cell-type-specific single-cell expression across 85 cell-type x developmental-timepoint combinations during embryogenesis.
DNA & GeneSingle-cell22OpennessOryzaG3
———A 700M-parameter DNA language model pretrained on the rice pangenome, built as a reusable foundation model for crop genomics and molecular breeding.
DNA & Gene19OpennessC3P
———Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.
DNA & Gene77OpennessGenos-m
20—177A 4.7B-parameter Mixture-of-Experts genomic foundation model pretrained on ~1.2 trillion nucleotide tokens from human-associated microbial genomes.
DNA & Gene73OpennessPlasmidLM
———A promptable DNA language model that generates multi-kilobase plasmid sequences from human-readable component specifications, post-trained with verifiable rewards.
DNA & Gene49OpennessDamageFormer
1——Multimodal deep-learning framework that detects and localizes DNA lesions directly from native nanopore sequencing, built on the damage-aware LesionBERT foundation model.
DNA & Gene45OpennessBio-BLIP
———A multimodal Q-former that fuses DNA sequence, gene context, protein function, and text into a prefix for a frozen LLM, enabling zero-shot genetic variant interpretation.
DNA & GeneLanguage model23OpennessOmniGene-4
———A unified bio-language Mixture-of-Experts foundation model spanning DNA, protein sequence and structure, and biological text, applied across eight task families from a single checkpoint.
Language modelDNA & GeneProtein7OpennessSusagi
7—3A permutation-invariant denoising transformer trained on ~2 million bacterial community samples to learn member-level stability scores and predict microbiome composition dynamics zero-shot.
DNA & Gene48OpennessWisteria
———A pretrained DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier-based attention to capture multi-scale genomic regulatory patterns.
DNA & Gene10OpennessWaypoint
———A family of GPT-2-style causal language models pretrained on 539,000+ microbiome samples, enabling zero- and few-shot transfer across microbiome prediction tasks.
DNA & Gene23OpennessCarbon
193—7.4KAn open autoregressive genomic foundation model (0.5B–8B params) with a 6-mer DNA tokenizer, matching Evo2-7B win rates at far higher throughput.
DNA & Gene93OpennessMIMIC
30——Generative multimodal foundation model that jointly models DNA, RNA, protein, and cellular context across six biological modalities, with SOTA splicing prediction.
RNAProteinDNA & Gene16OpennessGenNA
———An autoregressive nucleotide-and-text foundation model pretrained on ~416B characters from 2,221 eukaryotic species for natural-language-guided conditional generation of DNA and RNA sequences.
DNA & GeneRNA16OpennessOneGenome-Rice
19—135A 1.25B-parameter Mixture-of-Experts genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window.
DNA & Gene90OpennessOmniNA
—25Self-supervised generative foundation model jointly trained on 91.7M nucleotide sequences and structured annotations spanning 1.076 trillion bases, achieving SOTA on 23 nucleotide-language benchmarks.
DNA & Gene42OpennessDeep-Plant
1——A supervised, chromatin-informed foundation model that predicts regulatory activity directly from plant genomic sequence in Arabidopsis and rice.
DNA & Gene87Openness